Cryosurgery
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Summary: Cryosurgery with liquid nitrogen |
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Description:
Cryosurgery with liquid nitrogen. |
Want to know more or talk to a doctor? Come visit us at: Shim Clinic, Singapore
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Latest News:
Effect of aberrant vasculature during cryosurgery for prostate cancer. Tue, 30 Dec 2008 05:00:00 +0100 | Urology Effect of Aberrant Vasculature During Cryosurgery for Prostate Cancer. Urology. 2008 Dec 30; Authors: Jones JS Efficacy of cryosurgery for treatment of prostate cancer is based on completely freezing the prostate and all malignant tissues. The image from this patient demonstrates aberrant periprostatic vascular anatomy featuring two vessels that created a "heat sink" that overcame the outer extension of the ice ball, resulting in potential incomplete freeze in the area of the vessels. PMID: 19118887 [PubMed - as supplied by publisher] (Source: Urology) Cryosurgery combined with iodine-125 seed implantation in the treatment of unresectable lung cancer Sat, 20 Dec 2008 04:17:36 +0100 | Chinese Journal of Lung Cancer Conclusion Cryosurgery combined with iodine-125 seed implantation is effective in treating unresectable lung cancer, providing a promising treatment protocol for unresectable lung cancer patients. (Source: Chinese Journal of Lung Cancer) Computerized planning of prostate cryosurgery using variable cryoprobe insertion depth. Wed, 10 Dec 2008 05:00:00 +0100 | Cryobiology This study is a part of an ongoing effort to develop computerized tools for cryosurgery. Based on typical clinical practices, previous automated planning schemes have required that all cryoprobes be aligned at a single insertion depth. The current study investigates the benefit of removing this constraint, in comparison with results based on uniform insertion depth planning as well as the so-called "pullback procedure". Planning is based on the so-called "bubble-packing method", and its quality is evaluated with bioheat transfer simulations. This study is based on five 3D prostate models, reconstructed from ultrasound imaging, and cryoprobe active length in the range of 15-35mm. The variable insertion depth technique is found to consistently provide superior results when compared to the ot... Prostate cryotherapy monitoring using vibroacoustography: preliminary results of an ex vivo study and technical feasibility Tue, 04 Nov 2008 05:00:00 +0100 | IEEE Transactions on Biomedical Engineering In conclusion, this pilot study shows that VA produces clear images of a frozen prostate at different temperature stages. The frozen tissue appears as a uniform region with well-defined borders that are readily identified. These characteristic images should allow safer and more efficient application of prostatic cryosurgery. These results provide substantial motivation to further investigate VA as a potential modality to monitor prostate cryotherapy intraoperatively. (Source: IEEE Transactions on Biomedical Engineering) [intraoperative argon cryosurgery in surgical resection of advanced hepatic carcinoma: safety and efficacy.] Sat, 01 Nov 2008 04:00:00 +0100 | Journal of Southern Medical University CONCLUSIONS: Argon cryosurgery offers an effective and safe option for management of advanced hepatic carcinoma, and its combination with other therapeutic approaches may achieve better clinical effects. PMID: 19033121 [PubMed - in process] (Source: Journal of Southern Medical University) Best practice statement on cryosurgery for the treatment of localized prostate cancer Thu, 09 Oct 2008 15:01:47 +0100 | The Journal of Urology The protracted natural history of clinically localized prostate cancer has confounded the development of a national consensus regarding the optimal treatment for this disease. In the AUA 2007 Guideline for the Management of Clinically Localized Prostate Cancer: 2007 Update, multiple treatment modalities are considered as options. This conundrum is further complicated by stage migration and lead time bias, both associated with PSA-based early detection strategies and the resultant increase in the detection of small volume clinically localized cancers. Since the majority of men currently diagnosed with prostate cancer are likely to have the disease eradicated by one of several treatment modalities, the clinical focus on HRQL associated with treatment has intensified. There are no published l... Cryosurgery for prostate cancer Thu, 09 Oct 2008 15:00:37 +0100 | The Journal of Urology Is hot or cold cryosurgery a treatment alternative for men with localized prostate cancer? To evaluate this question the American Urological Association (AUA) assembled a panel of experts and the result of their work is a Best Practice Statement published in this issue of The Journal (page 1993). (Source: The Journal of Urology) American urological association releases best practice statement on cryosurgery for the treatment of localized prostate cancer Mon, 22 Sep 2008 17:00:00 +0100 | Health News from Medical News Today When the American Urological Association (AUA) guideline on the Management of Clinically Localized Prostate Cancer: 2007 Update was published, insufficient information was available to include cryosurgery in the data analysis. (Source: Health News from Medical News Today) American urological association releases best practice statement on cryosurgery Mon, 22 Sep 2008 04:00:00 +0100 | EurekAlert! - Cancer (Elsevier Health Sciences) A panel of experts convened by the American Urological Association to develop a best practice statement reached a consensus that primary cryosurgery is an option for men who have clinically organ confined prostate cancer of any grade with negative metastatic evaluation. Clinicians using cryosurgery are advised to review this best practice statement, which is published in the November 2008 issue of the Journal of Urology. (Source: EurekAlert! - Cancer) Prostate-sparing targeted therapies (cryotherapy and hifu) Fri, 19 Sep 2008 13:00:00 +0100 | Cancer / Oncology News From Medical News Today BERLIN, GERMANY (UroToday.com) - Focal prostate cancer therapy utilizing cryosurgery was reviewed by Dr. Ivan Colon, Assistant Professor of Urology, SUNY Downstate Medical School, and the use of HIFU for this indication was discussed by Dr. Ivan Grunberger, Associate Clinical Professor of Urology SUNY Downstate Medical School and Chief, Division of Urology New York Methodist Hospital. The conclusions of their presentations were very similar. (Source: Cancer / Oncology News From Medical News Today) Prospective evaluation of sexual function in patients receiving cryosurgery as a primary radical treatment for localized prostate cancer Fri, 12 Sep 2008 04:00:00 +0100 | BJU International To evaluate prospectively the sexual function of patients undergoing cryosurgery as a primary radical treatment for localized prostate cancer, as the development of 17 G cryotherapy probes has improved the delivery of this treatment, but one of the side-effects of cryosurgery is the development of erectile dysfunction (ED). Between July 2003 and May 2008, 53 patients were treated using an argon-based third-generation cryotherapy system (Oncura, Arlington Heights, IL, USA). Prospective data were collected at 6 weeks, 3 months, then 3-monthly up to 1 year and subsequently 6-monthly. Patients were followed up for up to 54 months, with a median (mean) follow-up 36 (30.5) months. All 53 patients were followed after receiving cryosurgery as primary treatment for prostate cancer; 51 (96.3%) had E... Recurring tracheal papillomatosis treated with cryosurgery. Sat, 06 Sep 2008 09:43:28 +0100 | Southern Medical Journal Cryosurgery has proven effective in managing malignant tracheobronchial tumors, yet its role in benign lesions, especially recurrent respiratory papillomatosis, is not well established. A case of isolated tracheal papillomas recurring 15 years following laser surgery is reported. Cryosurgery allowed improvement in symptoms and adequate control of the papillomas.Page: 967DOI: 10.1097/SMJ.0b013e31817ec397Authors: Mohan, Kinila T. MBBS, MD, FACP; Greenheck, Jennifer MSN APRN; Rubio, Edmundo R. MD (Source: Southern Medical Journal) Galil medical - galil medical warming catheter - class 2 recall Wed, 03 Sep 2008 04:30:10 +0100 | Medical Device Recalls since July 07, 2006 Urethral Warming System-Galil Medical Warming Catheter. The product is contained within prostate kits. This product is used in cryosurgery to prevent freezing of tissue. (Source: Medical Device Recalls since July 07, 2006) Intralesional cryosurgery for the treatment of hypertrophic scars and keloids following aesthetic surgery: the results of a prospective observational study Thu, 28 Aug 2008 04:00:00 +0100 | The International Journal of Lower Extremity Wounds This study was designed to evaluate the efficacy of this technology in the treatment of such scars and to assess the reduction of dissatisfaction. Eleven scars (on 11 patients) were treated by intralesional cryosurgery, following breast surgery, otoplasty, face-lifting, and brachioplasty. Each patient scored the concern from the scar and the scar deformity (scale from 1 to 5) prior and following treatment (higher score represents least satisfaction and a severe deformity). The follow-up period was between 3 months and 8 years. The results demonstrated a significant reduction in concern and deformity scores compared with before the cryotreatment (P = .001). The intralesional cryosurgery technique provides the plastic surgeon with an effective instrument to treat hypertrophic scars and keloi... Combined surgical method of orbital and periorbital hemangioma treatment in infants. Fri, 22 Aug 2008 13:33:13 +0100 | Orbit CONCLUSION: Combined surgical method of treatment of progressive capillary hemangiomas by using cryosurgery and surgical excision in infants allows the choice of optimum tactics depending on features of the course and clinical picture in each individual case and provides achievement of high cosmetic and functional result of treatment. The early beginning of treatment in cases of fast progressing of the tumor allows prevention of extensive skin affection and amblyopia development. PMID: 18716962 [PubMed - in process] (Source: Orbit) Combination of cryosurgery and argon plasma coagulation in rigid bronchoscope for treatment of main airway neoplasma Tue, 19 Aug 2008 07:53:13 +0100 | Chinese Journal of Lung Cancer (Source: Chinese Journal of Lung Cancer) Oncological and functional results of cryosurgical therapy of enchondromas and chondrosarcomas grade 1 Wed, 30 Jul 2008 04:00:00 +0100 | Journal of Surgical Oncology The objective of this study is to analyze the oncological and functional results.We studied the oncological and functional results of curettage and cryosurgery in 123 patients with 130 tumors. There were 75 enchondromas and 55 chondrosarcomas grade 1. The minimal follow-up period for all patients was 2 years (range 24-119 months).During follow-up one local recurrence of an active enchondroma and one local recurrence of an aggressive enchondroma occurred. They were treated with curettage and cryosurgery again. Both patients were disease-free at minimum of 3 years follow-up. No local recurrences after treatment of chondrosarcoma grade 1 were seen. Functional scores, according to the MSTS scoring system, showed an average score of 28 points (94%) at 2 years follow-up. Post-operative fractures... The performance of 17-gauge cryoprobes in vitro. Thu, 24 Jul 2008 11:19:28 +0100 | Technology in Cancer Research and Treatment In conclusion, the performance of cryoprobes differs depending on the medium and measuring device used. Cryoprobes deliver reproducible freeze cycles, although there is variation between different cryoprobes. In a multiprobe configuration performance seems less variable. PMID: 18642970 [PubMed - in process] (Source: Technology in Cancer Research and Treatment) Stability changes after cryosurgery in long tubular bones in correlation to histological results: an animal trial Thu, 24 Jul 2008 08:57:24 +0100 | Archives of Orthopaedic and Trauma Surgery This study utilizing a sheep model should prove the possible reduction of potential fracture while using a new miniature cryoprobe minimizing tissue damage and providing accurate control of the ablation process. Furthermore, postoperative histological changes should be investigated and the results correlated with the stability trials. Methods In 24 sheep, ablation of the femur and the tibial bone on one side was carried out. Ablation of the right femur was limited to an area of 2 cm2 with single cortical bone, whereas at the left tibia the whole proximal tibial plateau was included. The other side served as a control entity without cryoablation. After a period of 2, 4, and 6 months postoperative investigation of bending resistance of the femoral bone and o... Giant superficial basal cell carcinoma treated with cryosurgery Thu, 24 Jul 2008 04:00:00 +0100 | Dermatologic Surgery (Source: Dermatologic Surgery) In vivo colocalization of antigen and cytidyl guanosyl within dendritic cells is associated with the efficacy of cancer immunotherapy Tue, 01 Jul 2008 04:00:00 +0100 | Cancer Research Immunostimulatory cytidyl guanosyl (CpG) motifs are of great interest as cancer vaccine adjuvants. They act as potent inducers of Th1 responses, including the activation of cytotoxic CD8+ T lymphocytes (CTL). Whereas animal models have provided clear evidence that CpG enhances antitumor immunity, clinical trials in humans have thus far been less successful. Applying cryosurgery as an instant in situ tumor destruction technique, we now show that timing of CpG administration crucially affects colocalization of antigen and CpG within EEA-1+ and LAMP-1+ compartments within dendritic cells in vivo. Moreover, antigen/CpG colocalization is directly correlated with antigen cross-presentation, the presence of CTL, and protective antitumor immunity. Thus, failure or success of CpG as a vaccine adjuv... Clinical study of cryosurgery efficacy in the treatment of skin and subcutaneous tumors in dogs and cats. Tue, 01 Jul 2008 04:00:00 +0100 | Veterinary Surgery CONCLUSION: Cryosurgery is an efficient method for treatment of skin and subcutaneous tumors in dogs and cats. CLINICAL RELEVANCE: Cryosurgical ablation is an effective means of treating small cutaneous or subcutaneous tumors in dogs and cats, especially in older animals where wound closure or cosmetic outcome might limit surgical excision alone. PMID: 18986310 [PubMed - in process] (Source: Veterinary Surgery) Acu-vib Wed, 25 Jun 2008 00:00:00 +0100 | Hospital Management Acu-Vib is an Australian owned and operated company, with their head office located in the Sydney suburb of Castle Hill, New South Wales. Acu-Vib specializes in the distribution of high quality electronic test and monitoring equipment. These products are used in the fields of medicine, acoustics and vibrations, occupational health and safety, the environment, research and development. Acu-Vib medical equipment offers an extensive range of healthcare products to predominately ICU, emergency, surgical and general practice settings. Products include patient monitors, ECG, defibrillators, specialized surgical instruments, spirometers and audiometers. The excellent quality surgical products are tailored for gynaecology, proctology, phlebotomy, ophthalmology and dermatology specialities. Thes... Initial experience in renal cryosurgery for large renal lesions Sat, 14 Jun 2008 08:00:00 +0100 | Health News from Medical News Today ORLANDO, FL (UroToday.com) - Cryoablation of small renal masses (i.e. T1a (Source: Health News from Medical News Today) Immunologic response to primary cryoablation of high-risk prostate cancer. Fri, 13 Jun 2008 04:00:00 +0100 | Cryobiology Conclusion: Cryoablation of prostate cancer can improve tumor-specific cytotoxic T-cell stimulation with a dramatically increased tumor specific cytolytic activity. However, the response is not sufficiently maintained to prevent cancer relapse. PMID: 18593573 [PubMed - as supplied by publisher] (Source: Cryobiology) An amino acidic adjuvant to augment cryoinjury of mcf-7 breast cancer cells. Sat, 07 Jun 2008 04:00:00 +0100 | Cryobiology An amino acidic adjuvant to augment cryoinjury of MCF-7 breast cancer cells. Cryobiology. 2008 Jun 7; Authors: Wang CL, Teo KY, Han B One of the major challenges in cryosurgery is to minimize incomplete cryodestruction near the edge of the iceball. In the present study, the feasibility and effectiveness of an amino acidic adjuvant, glycine was investigated to enhance the cryodestruction of MCF-7 human breast cancer cell at mild freezing/thawing conditions via eutectic solidification. The effects of glycine addition on the phase change characteristics of NaCl-water binary mixture were investigated with a differential scanning calorimeter and cryo-macro/microscope. The results confirmed that a NaCl-glycine-water mixture has two distinct eutectic phase change events - binary eutec... [original articles] cryoablation for surgical treatment of chronic atrial fibrillation combined with mitral valve surgery: a clinical observation Fri, 30 May 2008 04:00:00 +0100 | European Journal of Cardio-Thoracic Surgery Conclusion: Although in this study the efficacy rate of cryoablative surgery was not the same as classical Cox-Maze III, it seems that this procedure is safe, simple, cost-effective and at the same time does not increase the operative time significantly. Using cryoablation may enhance the cure rate of chronic AF during mitral valve surgery. (Source: European Journal of Cardio-Thoracic Surgery) Quick-freeze procedure to heal a heel Tue, 27 May 2008 01:24:00 +0100 | WSJ.com: Health Many podiatrists say they can relieve chronic heel pain with cryosurgery, in which a frozen probe is inserted briefly in the painful area. Physicians say the procedure is safe, but some argue the evidence that it works is inadequate. (Source: WSJ.com: Health) Cryosurgery during topical imiquimod: a successful combination modality for lentigo maligna Mon, 14 Apr 2008 23:01:38 +0100 | International Journal of Dermatology We report a patient with lentigo maligna, who was treated with the combination of topical ... (Source: International Journal of Dermatology) Long-term prostate cryosurgery survival rates examined Mon, 31 Mar 2008 00:00:00 +0100 | MedWire News - Oncology Prostate cancer patients treated with percutaneous prostate cryosurgery monotherapy have similar biochemical disease-free survival rates to patients treated with other forms of non-extirpative monotherapies, say US scientists. (Source: MedWire News - Oncology) Long-term prostate cryosurgery survival rates examined Mon, 31 Mar 2008 00:00:00 +0100 | MedWire News - Prostate Cancer Prostate cancer patients treated with percutaneous prostate cryosurgery monotherapy have similar biochemical disease-free survival rates to patients treated with other forms of non-extirpative monotherapies, say US scientists. (Source: MedWire News - Prostate Cancer) In vivo detection of cryosurgery using multiphoton and harmonic generation microscopy. Sat, 29 Mar 2008 04:00:00 +0100 | Medical Engineering and Physics In this study, we use multimodal multiphoton microscopy to assess the change of extracellular matrix after cryotreatment of skin. The cellular matrix transformations and the intercellular interactions during the wound healing process after cryolesion for mice were measured in vivo and in real-time through the dorsal skinfold chamber (DSC). Intrinsic second-harmonic generation (SHG) signals from fibrillar collagen and two-photon excited (TPE) autofluorescence from cell were collected to investigate the cryosurgical response in vivo. The TPE and SHG signals are significantly different between normal and cryotreated mice, and correlates with the wound healing process. The results suggest that this approach may be applied in real-time to noninvasively monitor the cryosurgery process and could ... Letter: a cryosurgeon's viewpoint of excision vs. cryosurgery or basal cell carcinomas Thu, 27 Mar 2008 06:06:11 +0100 | Dermatologic Surgery Dermatologic Surgery, Volume 34, Issue 4, Page 582, April 2008. (Source: Dermatologic Surgery) Prostate cryosurgery effective primary treatment for prostate cancer Tue, 25 Mar 2008 00:00:00 +0100 | MedWire News - Consumer Health Results of a long-term study demonstrate that freezing prostate tissue to kill cancer cells may be as effective as standard prostate cancer treatments. (Source: MedWire News - Consumer Health) Healthtronics to acquire urological cryosurgery services provider Thu, 20 Mar 2008 16:45:23 +0100 | AuntMinnie.com Headlines Healthcare firm HealthTronics has brokered a deal to acquire Advanced Medical Partners (AMPI), a urological cryosurgery services company, the firm reported. (Source: AuntMinnie.com Headlines) Basal cell carcinoma Tue, 18 Mar 2008 04:00:00 +0100 | Clinical Evidence New condition. New options added for Cryotherapy/cryosurgery, Curettage and cautery/electrodesiccation, Imiquimod 5% cream, Photodynamic therapy , Surgery (excisional or Moh's micrographic surgery) , Fluorouracil, Cryotherapy/cryosurgery, Curettage and cautery/electrodesiccation, Photodynamic therapy, Surgery (conventional or Moh's micrographic surgery), Fluorouracil and Imiquimod 5% cream. (Source: Clinical Evidence) A pilot study on combination of cryosurgery and (125)iodine seed implantation for treatment of locally advanced pancreatic cancer. Wed, 12 Mar 2008 19:28:57 +0100 | World Journal of Gastroenterology CONCLUSION: Cryosurgery, which is far less invasive than conventional pancreatic resection, and is associated with a low rate of adverse effects, should be the treatment of choice for patients with locally advanced pancreatic cancer. (125)Iodine seed implantation can destroy the residual surviving cancer cells after cryosurgery. Hence, a combination of both modalities has a complementary effect. PMID: 18330956 [PubMed - in process] (Source: World Journal of Gastroenterology) Fibrous dysplasia of the mandible: surgical treatment with platelet-rich plasma and a corticocancellous iliac crest graft-report of a case. Tue, 11 Mar 2008 21:37:34 +0100 | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics Fibrous dysplasia of the mandible: Surgical treatment with platelet-rich plasma and a corticocancellous iliac crest graft-report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Apr;105(4):e12-8 Authors: Mendonça Caridad JJ, Platas F This paper reports on an alternative treatment method for mandibular reconstruction in a very rare symptomatic adult form of fibrous dysplasia. The treatment included excision of all the dysplastic tissue excluding the inner cortex and the lower border of the mandible, where cryosurgery was applied. Platelet-rich plasma was added to the autogenous bone and used to fill dead spaces and interfaces. Three months after reconstruction, implants were inserted in the hard dense bone that showed no resorption. Seven years after surger... Percutaneous cryosurgery for the treatment of hepatic colorectal metastases. Fri, 07 Mar 2008 05:00:00 +0100 | World Journal of Gastroenterology CONCLUSION: Percutaneous cryosurgery was a safe modality for hepatic colorectal metastases. Rather than an alternative to resection, this technique should be regarded as a complement to hepatectomy and as an additional means of achieving tumor eradication when total excision is not possible. PMID: 18322961 [PubMed - in process] (Source: World Journal of Gastroenterology) Key issues in bioheat transfer simulations for the application of cryosurgery planning. Fri, 29 Feb 2008 05:00:00 +0100 | Cryobiology Authors: Rabin Y The bioheat transfer simulation is undoubtedly the foundation for developing computerized tools for cryosurgery planning and analysis. While a large variety of techniques for bioheat transfer simulations are available in the literature of the past several decades, it is only their integration with clinical criteria and constraints which can make computerized planning a practical reality. This brief communication outlines (in the opinion of this author) the key issues that must be addressed in the application of bioheat transfer to cryosurgery planning and analysis, while drawing attention to recent and relevant publications in other journals, with reference to the most recent publication on the topic in the Journal of Cryobiology [Z. Magalov, A. Shitzer, D. Degani, Iso... A cryosurgeon's viewpoint of excision vs. cryosurgery or basal cell carcinomas Thu, 31 Jan 2008 14:55:55 +0100 | Dermatologic Surgery Dermatologic Surgery, Volume 0, Issue 0, Page ???, OnlineEarly Articles. (Source: Dermatologic Surgery) Cryosurgery with combination of 125iodine seed implantation for the treatment of locally advanced pancreatic cancer Thu, 31 Jan 2008 06:53:50 +0100 | Chinese Journal of Digestive Diseases Journal of Digestive Diseases, Volume 9, Issue 1, Page 32-40, February 2008. OBJECTIVE: To study the therapeutic value of cryosurgery with combination of 125iodine seed implantation for locally advanced pancreatic cancer. METHODS: Thirty-eight patients with locally advanced pancreatic cancer were enrolled in this study. The ... (Source: Chinese Journal of Digestive Diseases) Follow-up of renal masses after cryosurgery using computed tomography; enhancement patterns and cryolesion size Thu, 24 Jan 2008 13:17:23 +0100 | BJU International BJU International, Volume 0, Issue 0, Page ???, OnlineEarly Articles. OBJECTIVES To describe the characteristics of cryolesions as seen on computed tomography (CT), for size and enhancement patterns, and to assess correlations between these imaging findings and histopathological diagnosis, as in renal cryosurgery the ... (Source: BJU International) Single center experience with third-generation cryosurgery for management of organ-confined prostate cancer: critical evaluation of short-term outcomes, complications, and patient quality of life Thu, 10 Jan 2008 15:20:07 +0100 | Journal of Endourology Journal of Endourology Dec 2007, Vol. 21, No. 12: 1521-1532. Background and Purpose: Technical refinements such as improved ultrasonographic localization and the routine use of urethral warmers and small-gauge needle delivery systems have renewed interest in cryosurgical treatment as a minimally invasive option ... (Source: Journal of Endourology) Florida hospital doctor recognized for cryosurgery work Fri, 28 Dec 2007 19:10:23 +0100 | bizjournals.com Health Care:Hospitals headlines Dr. Gary Onik, director of Florida Hospital Celebration Health's prostate cancer research program, was recently awarded the gold award by the International Society of Cryosurgery. (Source: bizjournals.com Health Care:Hospitals headlines) Florida hospital doctor recognized for cryosurgery work Fri, 28 Dec 2007 19:10:23 +0100 | bizjournals.com Health Care:Pharmaceuticals headlines Dr. Gary Onik, director of Florida Hospital Celebration Health's prostate cancer research program, was recently awarded the gold award by the International Society of Cryosurgery. (Source: bizjournals.com Health Care:Pharmaceuticals headlines) Global approach to hepatic metastases from colorectal cancer: indication and outcome of intra-arterial chemotherapy and other hepatic-directed treatments Thu, 27 Dec 2007 17:21:09 +0100 | Medical Oncology Abstract Liver metastases of colorectal cancer is present in more than 20% of new diagnosed patients and in 40–60% of relapsed patients. It is a life-threatening prognostic aspect. Hepatic resection, when possible, is the best therapeutic modality, although the overall survival rate is still low (30%). Angiography and intraoperative ultrasonography are useful for resection. The number of hepatic metastases and the surgical margin are probably the most significant prognostic factors. Colorectal cancer may spread predominantly to the liver making regional treatment strategies viable options. Subtotal hepatic resections and segmentectomies are potentially curable procedures for single or small numbers of hepatic metastases without other sites of disease. However, there have... Fifteen years of bone tumor cryosurgery: a single-center experience of 440 procedures and long-term follow-up. Sat, 22 Dec 2007 05:00:00 +0100 | European Journal of Surgical Oncology CONCLUSIONS: Bone cryosurgery is a safe and effective limb-, joint- and even epiphysis-sparing surgical technique in suitable types of bone tumors, temporarily or permanently obviating the need for resection surgery. PMID: 18158228 [PubMed - as supplied by publisher] (Source: European Journal of Surgical Oncology) Cryosurgical ablation of hepatic colorectal metastases. Mon, 03 Dec 2007 05:00:00 +0100 | Surgical Oncology Authors: Paganini AM, Rotundo A, Barchetti L, Lezoche E Hepatic resection is the treatment of choice for primary and secondary hepatic tumors but only 15-25% of patients with hepatic colorectal metastases are eligible for a curative hepatic resection. Cryosurgical ablation (CSA) is employed when curative resection of metastases cannot be obtained. Sixty-four patients (35 males, 29 females, mean age 58.8 years, range 30-79 years) with hepatic colorectal metastases underwent CSA, under laparoscopic control (15 cases) or with open surgery (49 cases), with subsequent close follow-up. Intraoperative bleeding occurred in 32 out of 49 patients in the open group and only in 2 patients in the laparoscopic group. Minor morbidity that resolved with conservative treatment was 54.8% in the open gro... Cryoablation continues to show good results for kidney cancer patients Mon, 26 Nov 2007 08:00:00 +0100 | Cancer / Oncology News From Medical News Today A review of 62 Mayo Clinic patients who underwent cryoablation to treat cancerous kidney tumors shows that the patients are cancer free for up to two and a half years after having had the procedure. Also called cryotherapy or cryosurgery, cryoablation is a procedure in which extreme cold is applied to the tumor using a cryoprobe, a hollow needle-like device filled with argon gas. The gas rapidly freezes the targeted tumor. [click link for full article] (Source: Cancer / Oncology News From Medical News Today) |